TCCSG 論文発表（1991年～）

Keino D, Kinoshita A, Tomizawa D, Takahashi H, Ida K, Kurosawa H, Koike K, Ota S, Iwasaki N, Fujimura J, Yuza Y, Kiyotani C, Yamamoto S, Osumi T, Ueda T, Mochizuki S, Isoyama K, Hanada R, Tawa A, Manabe A, Toguchi Y, Ohara A.

Residual disease detected by multidimensional flow cytometry shows prognostic significance in childhood acute myeloid leukemia with intermediate cytogenetics and negative FLT3-ITD: a report from the Tokyo Children's Cancer Study Group.

Int J Hematol. 2016 Apr;103(4):416-22. doi: 10.1007/s12185-016-1937-y. Epub 2016 Jan 18. PMID: 26781613.

Tomizawa D, Kato M, Takahashi H, Fujimura J, Inukai T, Fukushima T, Kiyokawa N, Koh K, Manabe A, Ohara A. Favorable outcome in non-infant children with MLL-AF4-positive acute lymphoblastic leukemia: a report from the Tokyo Children's Cancer Study Group.

Int J Hematol 102:602-10, 2015（PubMed）

Kato M, Manabe A, Saito AM, Koh K, Inukai T, Ogawa C, Goto H, Tsuchida M, Ohara A. Outcome of pediatric acute lymphoblastic leukemia with very late relapse: a retrospective analysis by the Tokyo Children's Caner Study Group (TCCSG).

Int J Hematol 101:52-7、2015（PubMed）

Kato M, Manabe A, Koh K, Inukai T, Kiyokawa N, Fukushima T, Goto H, Hasegawa D, Ogawa C, Koike K, Ota S, Noguchi Y, Kikuchi A, Tsuchida M, Ohara A. Treatment outcomes of adolescent acute lymphoblastic leukemia treated on Tokyo Children’s Cancer Study Group (TCCSG) clinical trials.

Int J Hematol 100: 180-7, 2014(PubMed)

Kato M, Imamura T, Manabe A, Hashii Y, Koh K, Sato A, Takahashi H, Hori H, Taki T, Inoue M, Hayashi Y, Horibe K, Tsuchida M, Kojima S, Oda M, Ohara A.

Prognostic impact of gained chromosomes in high-hyperdiploid childhood acute lymphoblastic leukaemia: a collaborative retrospective study of the Tokyo Children's Cancer Study Group and Japan Association of Childhood Leukaemia Study.

Br J Haematol. 164:376-83, 2014 (PubMed)

Buitenkamp TD, Izraeli S, Zimmermann M, Forestier E, Heerema NA, van den Heuvel-Eibrink MM, Pieters R, Korbijn CM, Silverman LB, Schmiegelow K, Liang DC, Horibe K, Arico M, Biondi A, Basso G, Rabin KR, Schrappe M, Cario G, Mann G, Morak M, Panzer-Grümayer R, Mondelaers V, Lammens T, Cavé H, Stark B, Ganmore I, Moorman AV, Vora A, Hunger SP, Pui CH, Mullighan CG,Manabe A, Escherich G, Kowalczyk JR, Whitlock JA, Zwaan CM.

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group.

Blood 123:70-7, 2014(PubMed)

Kato M, Koh K, Manabe A, Saito T, Hasegawa D, Isoyama K, Ki

noshita A, Maeda M, Okimoto Y, Kajiwara M, Kaneko T, Sugita K, Kikuchi K, Tsuchida T, Ohara A.

No impact of high-dose cytarabine and asparaginase as early intensification with intermediate-risk paediatric acute lymphoblastic leukaemia: results of randomized trial TCCSG study L99-15

Br J Haematol 164:376-83, 2014(PubMed)

Ishida Y, Maeda M, Urayama KY, Kiyotani C, Aoki Y, Kato Y, Goto S, Sakaguchi S, Sugita K, Tokuyama M, Nakadate N, Ishii E, Tsuchida M, Ohara A; The QOL committee of Tokyo Children's Cancer Study Group (TCCSG).

Secondary cancers among children with acute lymphoblastic leukaemia treated by the Tokyo Children's Cancer Study Group protocols: a retrospective cohort study.

Br J Haematol 164:101-112, 2014

Schmiegelow K, Levinsen MF, Attarbaschi A, Baruchel A, Devidas M, Escherich G,Gibson B, Heydrich C, Horibe K, Ishida Y, Liang DC, Locatelli F, Michel G,Pieters R, Piette C, Pui CH, Raimondi S, Silverman L, Stanulla M, Stark B, WinickN, Valsecchi MG.
Second malignant neoplasms after treatment of childhood acute lymphoblasticleukemia.
J Clin Oncol. 2013 Jul 1;31(19):2469-76. doi: 10.1200/JCO.2012.47.0500. Epub 2013May 20.

Schrappe M, Hunger SP, Pui CH, Saha V, Gaynon PS, Baruchel A, Conter V, Otten J, Ohara A, Versluys AB, Escherich G, Heyman M, Silverman LB, Horibe K, Mann G, Camitta BM, Harbott J, Riehm H, Richards S, Devidas M, Zimmermann M: Outcomes after induction failure in childhood acute lymphoblastic leukemia. N Engl J Med 366:1371-1381, 2012(PubMed)

Inukai T, Kiyokawa N, Campana D, Coustan-Smith E, Kikuchi A, Kobayashi M, Takahashi H, Koh K, Manabe A, Kumagai M, Ikuta K, Hayashi Y, Tsuchida M, Sugita K, Ohara A: Clinical significance of early T-cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children's Cancer Study Group Study L99-15. Br J Haematol 156:358-365, 2012(PubMed)

太田節雄, 神谷尚宏, 福島啓太郎, 齋藤正博, 山本将平, 小野敏明, 加藤宏美, 康勝好, 佐藤武幸, 熊谷昌明, 小原明, 土田昌宏: 血液・腫瘍疾患患児におけるインフルエンザA(H1N1)の影響ー新型インフルエンザ罹患情報共有システムの構築. 臨床血液 ５２:1759-1764,2011(PubMed)

Hasegawa D, Manabe A, Ohara A, Kikuchi A, Koh K, Kiyokawa N, Fukushima T, Ishida Y, Saito T, Hanada R, Tsuchida M: The utility of performing the initial lumbar puncture on day 8 in remission induction therapy for childhood acute lymphoblastic leukemia: TCCSG L99-15 study. Pediatr Blood Cancer 58:23-30, 2011(PubMed)

Goto H, Inukai T, Inoue H, Ogawa C, Fukushima T, Yabe M, Kikuchi A, Koike K, Fukushima K, Isoyama K, Saito T, Ohara A, Hanada R, Iwamoto J, Hotta N, Nagatoshi Y, Okamura J, Tsuchida M: Acute lymphoblastic leukemia and Down syndrome: the collaborative study of the Tokyo Children's Cancer Study Group and the Kyushu Yamaguchi Children's Cancer Study Group. Int J Hematol 93:192-198, 2011(PubMed)

Aricò M, Schrappe M, Hunger SP, Carroll WL, Conter V, Galimberti S, Manabe A, Saha V, Baruchel A, Vettenranta K, Horibe K, Benoit Y, Pieters R, Escherich G, Silverman LB, Pui CH, Valsecchi MG.

Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.

J Clin Oncol 28:4755-61, 2010

Tsucida M, Ohara A, Manabe A, Kumagai M, Shimada H, Kikuchi A, Mori T, Saito M, Akiyama M, Fukushima T, Koike K, Shiobara M, Ogawa C, Kanazawa T, Noguchi Y, Oota S, Okimoto Y, Yabe H, Kajiwara M, Tomizawa D, Ko K, Sugita K, Kaneko T, Maeda M, Inukai T, Goto H, Takahashi H, Isoyama K, Hayashi Y, Hosaya R, Hanada R, on behalf of Tokyo Children’s Cancer Study Group T, Japan: Long-term results of Tokyo Children’s Cancer Study Group trials for childhood acute lymphoblastic leukemia, 1984-1999. Leukemia 24:383-396, 2010(PubMed)

外松学, 金子隆, 齋藤正博, 野口靖, 高橋浩之, 矢部みはる, 真部淳, 小原明, 花田良二, 土田昌宏: 診断後早期の臓器障害併発のために臨床試験に参加できなかった重症ALL 7症例の臨床像の検討 TCCSG L99-15研究. 日本小児血液学会雑誌 24:25-31, 2010

Manabe A, Ohara A, Hasegawa D, Koh K, Saito T, Kiyokawa N, Kikuchi A, Takahashi H, Ikuta K, Hayashi Y, Hanada R, Tsuchida M: Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia: The Tokyo Children’s Cancer Study Group (TCCSG) Study L99-15. Haematologica 93:1155-1160, 2008(PubMed)

Kikuchi A, Mori T, Fujimoto J, Kumagai M, Sunami S, Okimoto Y, Tsuchida M.Outcome of childhood B-cell non-Hodgkin lymphoma and B-cell acute lymphoblasticleukemia treated with the Tokyo Children's Cancer Study Group NHL B9604 protocol. Leuk Lymphoma 49:757-62, 2008 PubMed

Kikuchi A, Maeda M, Hanada R, Okimoto Y, Ishimoto K, Kaneko T, Ikuta K,Tsuchida M; Tokyo Children's Cancer Study Group (TCCSG). Moyamoya syndromefollowing childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 48:268-72, 2007 PubMed

Tomizawa D, Tabuchi K, Kinoshita A, Hanada R, Kigasawa H, Tsukimoto I,Tsuchida M; Tokyo Children's Cancer Study Group. Repetitive cycles of high-dosecytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children'sCancer Study Group. Pediatr Blood Cancer 49:127-32, 2007 PubMed

Igarashi S, Manabe A, Ohara A, Kumagai M, Saito T, Okimoto Y, Kamijyo T, Isoyama K, Kajiwara S, Sotomatsu M, Sugita KI, Sugita K, Maeda M, Yabe H, Kinoshita A, Kaneko T, Hayashi Y, Ikuta K, Hanada R, Tsuchida M: No advantage of dexamethasone over prednisolone for the outcome of standard- and intermediate-risk childhood acute lymphoblastic leukemia in the Tokyo Children's Cancer Study Group L95-14 Protocol. Journal of Clinical Oncology 23:6489-6498, 2005(PubMed)

Mori T, Manabe A, Tsuchida M, Hanada R, Yabe H, Ohara A, Saito T, Nakazawa S. Allogeneic bone marrow transplantation in first remission rescues children withPhiladelphia chromosome-positive acute lymphoblastic leukemia: Tokyo Children'sCancer Study Group (TCCSG) studies L89-12 and L92-13. Med Pediatr Oncol 37:426-31, 2001. PubMed

Manabe A, Tsuchida M, Hanada R, Ikuta K, Toyoda Y, Okimoto Y, Ishimoto K, Okawa H, Ohara A, Kaneko T, Koike K, Sato T, Sugita K, Bessho F, Hoshi Y, Maeda M, Kinoshita A, Saito T, Tsunematsu Y, Nakazawa S: Delay of the Diagnostic Lumbar Puncture and Intrathecal Chemotherapy in Children with Acute Lymphoblastic Leukemia Who Undergo Routine Corticosteroid Testing:Tokyo Children's Cancer Study Group Study L89-12. J Clin Oncol 19:3182-3187, 2001(PubMed)

Toyoda Y, Manabe A, Tsuchida M, Hanada R, Ikuta K, Okimoto Y, Ohara A, Ohkawa Y, Mori T, Ishimoto K, Sato T, Kaneko T, Maeda M, Koike K-i, Shitara T, Hoshi Y, Hosoya R, Tsunematsu Y, Bessho F, Nakazawa S, Saito T: Six Months of Maintenance Chemotherapy After Intensified Treatment for Acute Lymphoblastic Leukemia of Childhood. J Clin Oncol 18:1508-1516, 2000(PubMed)

Tsuchida M, Ikuta K, Hanada R, Saito T, Isoyama K, Sugita K, Toyoda Y, Manabe A, Koike K, Kinoshita A, Maeda M, Ishimoto K, Sato T, Okimoto Y, Kaneko T, Kajiwara M, Sotomatsu M, Hayashi Y, Yabe H, Hosoya R, Hoshi Y, Ohira M, Bessho F, Tsunematsu Y, Tsukimoto I, Nakazawa S: Long-term follow-up of childhood acute lymphoblastic leukemia in Tokyo Children's Cancer Study Group 1981-1995. Leukemia 14:2295-2306, 2000 (PubMed)

Tsukada M, Komiyama A, Nakazawa S, Tsuchida M, Nishihira H, Shitara T, OhiraM, Tsunematsu Y, Yamamoto K, Hoshi Y, et al. Treatment of standard risk acutelymphoblastic leukemia in children with the Tokyo Children Cancer Study Group(TCCSG) L84-11 protocol in Japan. Int J Hematol.57:1-7,1993  PubMed

Tsuchida M, Akatsuka J, Bessho F, Chihara H, Hayashi Y, Hoshi Y, Hosoya R,Furukawa T, Ikuta K, Inana I, et al. Treatment of acute lymphoblastic leukemia inthe Tokyo Children's Cancer Study Group--preliminary results of L84-11 protocol. Acta Paediatr Jpn 33:522-32, 1991 PubMed

Bessho F, Kigasawa H, Tsuchida M, Tsukimoto I, Nakazawa S, Yamamoto M,Tsunematsu Y, Yamada K, Sugita K, Ohkawa Y, et al. Improved prognosis of acutenonlymphocytic leukemia in children: results of the 12th-ANLL protocol of TokyoChildren's Cancer Study Group. Acta Paediatr Jpn 33:533-9, 1991 PubMed